Longevity

The Dog Aging Project conducts rigorous scientific research designed to define, explain, and ameliorate the effects of aging. To achieve this mission, it has built a community of volunteers and researchers united by a shared love for dogs and committed to helping dogs and humans live longer, healthier lives — together.

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The Project aims to understand the biological and environmental factors that influence aging and intervene to prevent debilitating decline. Studying aging in humans is challenging and expensive, but dogs truly are science’s best friends. Even though they age more rapidly than humans, they experience the same diseases of aging, they are genetically diverse, and they share our environment. By studying aging in dogs, we can more quickly expand our knowledge of the aging process not just in dogs but in humans too!

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The Tiny Foundation is proud to support the Test of Rapamycin In Aging Dogs (TRIAD), a double-blind, placebo-controlled clinical trial of the mTOR inhibitor rapamycin, which at low doses has been shown to increase lifespan and delay or reverse many age-related disorders in mice. This is the third and largest trial of rapamycin that our group has conducted to date.

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The Dog Aging Project is an open science project committed to facilitating public access to de-identified data for many kinds of scientific inquiry. Researchers around the world can access Dog Aging Project data via Terra, a cloud computing platform hosted by the Broad Institute of MIT and Harvard.